STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) proteome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
FABZ_ECOLI
P0A6Q6
fabZ

sefA yaeA

b0180 JW0175
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase) (EC 4.2.1.-) (17 kDa actomyosin component)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic (Experimental)
N/A
 
TF
 
 
 
yes
yes
MIAB_ECOLI
P0AEI1
miaB

yleA

b0661 JW0658
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB (EC 2.-.-.-) (tRNA-i(6)A37 methylthiotransferase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GLGB_ECOLI
P07762
glgB
b3432 JW3395
1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Glycogen-branching enzyme) (BE)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MENA_ECOLI
P32166
menA

yiiW

b3930 JW3901
1,4-dihydroxy-2-naphthoate octaprenyltransferase (DHNA-octaprenyltransferase) (EC 2.5.1.74)
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein (Experimental)
IM (predicted)
 
SRP
SEC
 
 
yes
yes
AMPD_ECOLI
P13016
ampD
b0110 JW0106
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
HIS4_ECOLI
P10371
hisA
b2024 JW2006
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16) (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
PLSC_ECOLI
P26647
plsC

parF

b3018 JW2986
1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (EC 2.3.1.51) (EC 2.3.1.n4) (Lysophosphatidic acid acyltransferase) (LPAAT) (Phosphatidic acid synthase) (PA synthase)
Integral Inner Membrane
B
Cell inner membrane | Peripheral membrane protein
Membrane anchored (Experimental)
IM (predicted)
 
 
SEC
 
 
yes
yes
DXR_ECOLI
P45568
dxr

ispC yaeM

b0173 JW0168
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase)
Cytoplasmic
A
 
Cytoplasmic
IM (predicted-detected)
 
 
 
 
 
no
yes
DXS_ECOLI
P77488
dxs

yajP

b0420 JW0410
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
K1PF_ECOLI
P0AEW9
fruK

fpk

b2168 JW2155
1-phosphofructokinase (EC 2.7.1.56) (Fructose 1-phosphate kinase)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
CH10_ECOLI
P0A6F9
groS

groES mopB

b4142 JW4102
10 kDa chaperonin (Protein Cpn10) (groES protein)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
CPDB_ECOLI
P08331
cpdB
b4213 JW4171
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16)
Periplasmic
G
Secreted
Periplasmic (Experimental)
N/A
 
 
SEC
SurA
 
no
yes
LIGT_ECOLI
P37025
ligT

yadP

b0147 JW5011
2'-5'-RNA ligase (EC 6.5.1.-)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
DAPD_ECOLI
P0A9D8
dapD
b0166 JW0161
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GPMA_ECOLI
P62707
gpmA

gpm pgm pgmA

b0755 JW0738
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.1)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GPMI_ECOLI
P37689
gpmI

pgmI yibO

b3612 JW3587
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (BPG-independent PGAM) (Phosphoglyceromutase) (iPGM) (EC 5.4.2.1)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ENTA_ECOLI
P15047
entA
b0596 JW0588
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
MHPB_ECOLI
P0ABR9
mhpB
b0348 JW0339
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase (EC 1.13.11.16)
Cytoplasmic
A
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
DLGD_ECOLI
P37672
dlgD

yiaK

b3575 JW3547
2,3-diketo-L-gulonate reductase (2,3-DKG reductase) (EC 1.1.1.130) (3-dehydro-L-gulonate 2-dehydrogenase)
Cytoplasmic
A
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
YIAN_ECOLI
P37675
yiaN
b3578 JW5651
2,3-diketo-L-gulonate TRAP transporter large permease protein yiaN
Integral Inner Membrane
B
Cell inner membrane | Multi-pass membrane protein
Integral Membrane Protein
IM (predicted)
 
SRP
SEC
 
 
no
yes
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