STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) proteome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
FABZ_ECOLI
P0A6Q6
fabZ

sefA yaeA

b0180 JW0175
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase) (EC 4.2.1.-) (17 kDa actomyosin component)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic (Experimental)
N/A
 
TF
 
 
 
yes
yes
DXS_ECOLI
P77488
dxs

yajP

b0420 JW0410
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CH10_ECOLI
P0A6F9
groS

groES mopB

b4142 JW4102
10 kDa chaperonin (Protein Cpn10) (groES protein)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
no
yes
DAPD_ECOLI
P0A9D8
dapD
b0166 JW0161
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
GPMA_ECOLI
P62707
gpmA

gpm pgm pgmA

b0755 JW0738
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.1)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
KBL_ECOLI
P0AB77
kbl
b3617 JW3592
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (EC 2.3.1.29) (Glycine acetyltransferase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
UBIH_ECOLI
P25534
ubiH

visB

b2907 JW2875
2-octaprenyl-6-methoxyphenol hydroxylase (EC 1.14.13.-)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ODO1_ECOLI
P0AFG3
sucA
b0726 JW0715
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
TF
 
 
 
yes
yes
MENE_ECOLI
P37353
menE
b2260 JW2255
2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CYSQ_ECOLI
P22255
cysQ

amtA

b4214 JW4172
3'(2'),5'-bisphosphate nucleotidase cysQ (EC 3.1.3.7) (3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase) (3'-phosphoadenosine 5'-phosphate phosphatase) (PAP phosphatase) (DPNPase)
Peripheral inner membrane protein facing the cytoplasm
F1
CytoplasmCell inner membrane | Peripheral membrane protein | Cytoplasmic side
Membrane associated (Experimental)
N/A
 
 
 
 
 
no
yes
RIBB_ECOLI
P0A7J0
ribB

htrP

b3041 JW3009
3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell membrane | Peripheral membrane protein
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
KDSC_ECOLI
P0ABZ4
kdsC

yrbI yrbJ

b3198 JW3165
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic (Experimental)
N/A
 
 
 
 
 
yes
yes
FADI_ECOLI
P76503
fadI

yfcY

b2342 JW2339
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (ACSs) (Acetyl-CoA acyltransferase) (Acyl-CoA ligase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
UBID_ECOLI
P0AAB4
ubiD

yigC yigY

b3843 JW3819
3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylase)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell membrane | Peripheral membrane protein
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
FABG_ECOLI
P0AEK2
fabG
b1093 JW1079
3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABB_ECOLI
P0A953
fabB

fabC

b2323 JW2320
3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC 2.3.1.41) (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
FABF_ECOLI
P0AAI5
fabF

fabJ

b1095 JW1081
3-oxoacyl-[acyl-carrier-protein] synthase 2 (EC 2.3.1.179) (3-oxoacyl-[acyl-carrier-protein] synthase II) (Beta-ketoacyl-ACP synthase II) (KAS II)
Peripheral inner membrane protein facing the cytoplasm
F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
HSLO_ECOLI
P0A6Y5
hslO

yrfI

b3401 JW5692
33 kDa chaperonin (Heat shock protein 33) (HSP33)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
MALQ_ECOLI
P15977
malQ

malA

b3416 JW3379
4-alpha-glucanotransferase (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (D-enzyme)
Peripheral inner membrane protein facing the cytoplasm
F1
Cytoplasm
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
WECF_ECOLI
P56258
wecF

rffT yifM

b4481 JW5596
4-alpha-L-fucosyltransferase (EC 2.4.1.-) (TDP-Fuc4NAc:lipid II Fuc4NAc transferase) (Fuc4NAc transferase)
Peripheral inner membrane protein facing the cytoplasm
F1
Cell inner membrane | Peripheral membrane protein
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
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