STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) proteome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
IAP_ECOLI
P10423
iap
b2753 JW2723
Alkaline phosphatase isozyme conversion protein (EC 3.4.11.-)
Peripheral inner membrane protein facing the periplasm
F2
 
Membrane associated (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DMSA_ECOLI
P18775
dmsA
b0894 JW5118
Anaerobic dimethyl sulfoxide reductase chain A (DMSO reductase) (EC 1.8.99.-)
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane | Peripheral membrane protein | Cytoplasmic side
Periplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
DmsD
TAT,SEC
 
 
yes
yes
DMSB_ECOLI
P18776
dmsB
b0895 JW0878
Anaerobic dimethyl sulfoxide reductase chain B (DMSO reductase iron-sulfur subunit)
Peripheral inner membrane protein facing the periplasm
F2
 
Cytoplasmic
N/A
 
 
TAT piggyback
 
 
yes
yes
CUSB_ECOLI
P77239
cusB

ylcD

b0574 JW0563
Cation efflux system protein cusB
Peripheral inner membrane protein facing the periplasm
F2
 
Membrane anchored
N/A
 
 
SEC
 
 
yes
yes
DACA_ECOLI
P0AEB2
dacA

pfv

b0632 JW0627
D-alanyl-D-alanine carboxypeptidase dacA (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Beta-lactamase) (EC 3.5.2.6) (Penicillin-binding protein 5) (PBP-5)
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane | Peripheral membrane protein | Cytoplasmic side
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
DACB_ECOLI
P24228
dacB
b3182 JW3149
D-alanyl-D-alanine carboxypeptidase dacB (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (D-alanyl-D-alanine endopeptidase) (DD-endopeptidase) (EC 3.4.21.-) (Penicillin-binding protein 4) (PBP-4)
Peripheral inner membrane protein facing the periplasm
F2
Secreted
Membrane anchored (Experimental)
N/A
 
 
SEC
 
 
yes
yes
DACC_ECOLI
P08506
dacC
b0839 JW0823
D-alanyl-D-alanine carboxypeptidase dacC (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein 6) (PBP-6)
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane | Peripheral membrane protein
Membrane anchored (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
DACD_ECOLI
P33013
dacD

phsE yeeC

b2010 JW5329
D-alanyl-D-alanine carboxypeptidase dacD (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein 6b) (PBP-6b)
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane | Peripheral membrane protein
Membrane anchored (Experimental)
N/A
 
 
SEC
 
 
yes
yes
FLIE_ECOLI
P0A8T5
fliE

fla AI flaN

b1937 JW1921
Flagellar hook-basal body complex protein fliE
Peripheral inner membrane protein facing the periplasm
F2
Bacterial flagellum basal body
Cytoplasmic
N/A
flagellum
 
Flagellum
 
 
no
yes
FDNG_ECOLI
P24183
fdnG
b1474 JW1470
Formate dehydrogenase, nitrate-inducible, major subunit (EC 1.2.1.2) (Anaerobic formate dehydrogenase major subunit) (Formate dehydrogenase-N subunit alpha) (FDH-N subunit alpha)
Peripheral inner membrane protein facing the periplasm
F2
Secreted
Membrane associated (Experimental)
N/A
 
 
TAT
 
 
no
yes
MBHM_ECOLI
P0ACE0
hybC
b2994 JW2962
Hydrogenase-2 large chain (HYD2) (EC 1.12.99.6) (Membrane-bound hydrogenase 2 large subunit) (NiFe hydrogenase)
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane | Peripheral membrane protein
Periplasmic (Experimental)
Soluble protein detected in Inner Membrane Fraction
 
 
TAT piggyback
 
 
yes
yes
HYBA_ECOLI
P0AAJ8
hybA
b2996 JW2964
Hydrogenase-2 operon protein hybA
Peripheral inner membrane protein facing the periplasm
F2
Secreted
Periplasmic (Experimental)
IM (predicted)
 
 
TAT,SEC
 
 
yes
yes
MBHT_ECOLI
P69741
hybO

yghV

b2997 JW2965
Hydrogenase-2 small chain (HYD2) (EC 1.12.99.6) (Membrane-bound hydrogenase 2 small subunit) (NiFe hydrogenase)
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane | Peripheral membrane protein | Periplasmic sidePeriplasm
Membrane anchored (Experimental)
IM (predicted)
 
TF
TAT,SEC
 
 
yes
yes
MDTA_ECOLI
P76397
mdtA

yegM

b2074 JW5338
Multidrug resistance protein mdtA (Multidrug transporter mdtA)
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane | Peripheral membrane protein
Membrane anchored
N/A
 
 
SEC, non classical
 
 
yes
yes
CPXP_ECOLI
P0AE85
cpxP

yiiO

b4484 JW5558
Periplasmic protein CpxP
Peripheral inner membrane protein facing the periplasm
F2
Secreted
Membrane associated (Experimental)
N/A
 
 
SEC
 
 
yes
yes
YNFG_ECOLI
P0AAJ1
ynfG
b1589 JW1581
Probable anaerobic dimethyl sulfoxide reductase chain ynfG (DMSO reductase iron-sulfur subunit ynfG)
Peripheral inner membrane protein facing the periplasm
F2
 
Periplasmic
N/A
 
 
TAT piggyback
 
 
yes
yes
YNFF_ECOLI
P77783
ynfF
b1588 JW5260
Probable dimethyl sulfoxide reductase chain ynfF (DMSO reductase) (EC 1.8.99.-)
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane | Peripheral membrane protein | Cytoplasmic side
Periplasmic
N/A
 
 
TAT,SEC
 
 
yes
yes
YDGA_ECOLI
P77804
ydgA
b1614 JW1606
Protein ydgA
Peripheral inner membrane protein facing the periplasm
F2
Cell inner membrane | Peripheral membrane protein | Periplasmic side
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
SEC
 
 
yes
yes
YNFE_ECOLI
P77374
ynfE
b1587 JW1579
Putative dimethyl sulfoxide reductase chain ynfE (DMSO reductase) (EC 1.8.99.-)
Peripheral inner membrane protein facing the periplasm
F2
Cell membrane | Peripheral membrane protein | Cytoplasmic side
Periplasmic
N/A
 
 
TAT
 
 
yes
yes
YEDY_ECOLI
P76342
yedY
b1971 JW1954
Sulfoxide reductase catalytic subunit yedY (EC 1.8.-.-)
Peripheral inner membrane protein facing the periplasm
F2
Secreted
Membrane anchored (Experimental)
N/A
 
 
TAT,SEC
 
 
no
yes
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