STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) proteome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) proteome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
MCRB_ECOLI
P15005
mcrB

rglB

b4346 JW5871
5-methylcytosine-specific restriction enzyme B (EC 3.1.21.-) (EcoKMcrBC)
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ICLR_ECOLI
P16528
iclR
b4018 JW3978
Acetate operon repressor
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ATOC_ECOLI
Q06065
atoC

az

b2220 JW2214
Acetoacetate metabolism regulatory protein AtoC (Ornithine decarboxylase antizyme) (Ornithine/arginine decarboxylase inhibitor)
Nucleoid
N
Cytoplasm.
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ARCA_ECOLI
P0A9Q1
arcA

cpxC dye fexA msp seg sfrA

b4401 JW4364
Aerobic respiration control protein ArcA (Dye resistance protein)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
Cytoplasm
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
SYA_ECOLI
P00957
alaS

lovB

b2697 JW2667
Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
Cytoplasm
Cytoplasmic
N/A
 
TF
 
 
 
no
yes
ALKB_ECOLI
P05050
alkB

aidD

b2212 JW2200
Alpha-ketoglutarate-dependent dioxygenase AlkB (EC 1.14.11.-) (Alkylated DNA repair protein AlkB)
Nucleoid
N
 
Cytoplasmic
IM (predicted)
 
 
 
 
 
yes
yes
NORR_ECOLI
P37013
norR

ygaA

b2709 JW5843
Anaerobic nitric oxide reductase transcription regulator norR
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
RCSB_ECOLI
P0DMC7
rcsB
b2217 JW2205
Ankyrin repeat protein A (Ankyrin-like regulatory protein)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
MQSA_ECOLI
Q46864
mqsA

ygiT

b3021 JW2989
Antitoxin MqsA
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
no
yes
RELB_ECOLI
P0C079
relB
b1564 JW1556
Antitoxin RelB
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
no
no
ARAC_ECOLI
P0A9E0
araC
b0064 JW0063
Arabinose operon regulatory protein
Nucleoid
N
Cytoplasm.
Cytoplasmic
N/A
 
 
 
 
 
no
yes
ARGR_ECOLI
P0A6D0
argR

xerA

b3237 JW3206
Arginine repressor
Nucleoid
N
Cytoplasm.
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
ARSR_ECOLI
P37309
arsR

arsE

b3501 JW3468
Arsenical resistance operon repressor
Nucleoid
N
Cytoplasm.
Cytoplasmic
N/A
 
 
 
 
 
no
no
RECG_ECOLI
P24230
recG

radC

b3652 JW3627
ATP-dependent DNA helicase recG (EC 3.6.4.12)
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
REP_ECOLI
P09980
rep
b3778 JW5604
ATP-dependent DNA helicase rep (EC 3.6.4.12)
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
RHLB_ECOLI
P0A8J8
rhlB

mmrA

b3780 JW3753
ATP-dependent RNA helicase rhlB (EC 3.6.4.13)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
BIRA_ECOLI
P06709
birA

bioR dhbB

b3973 JW3941
Bifunctional protein BirA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. Deletion of BioR resulted in a 15-fold increase of bio operon transcription in the presence of high biotin levels.
Nucleoid, Integral Inner Membrane
N, B
 
Cytoplasmic
IM (predicted)
 
SRP
SEC
 
 
yes
yes
PUTA_ECOLI
P09546
putA

poaA

b1014 JW0999
Bifunctional protein putA [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.5.1.12)]
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
 
Cytoplasmic
Soluble protein detected in Inner Membrane Fraction
 
 
 
 
 
yes
yes
CDAR_ECOLI
P37047
cdaR

sdaR yaeG

b0162 JW5013
Carbohydrate diacid regulator (Sugar diacid regulator)
Nucleoid
N
 
Cytoplasmic
N/A
 
 
 
 
 
yes
yes
CRP_ECOLI
P0ACJ8
crp

cap csm

b3357 JW5702
Catabolite gene activator (cAMP receptor protein) (cAMP regulatory protein)
Nucleoid, Peripheral inner membrane protein facing the cytoplasm
N, F1
 
Cytoplasmic
N/A
 
TF
 
 
 
yes
yes
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