STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12 (MG1655) Secretome

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(Uniprot)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
YMGJ_ECOLI
A5A612
ymgJ
b4594
Uncharacterized membrane protein ypdK
Periplasmic
G
IM (predicted)
 
-
 
 
SEC
 
 
no
yes
YJBT_ECOLI
A5A628
yjbT
b4620
Uncharacterized protein yjbT
Periplasmic
G
N/A
 
-
 
 
SEC
 
 
no
yes
RZOQ_ECOLI
C1P601
rzoQ
b4689 JW1545.1
Uncharacterized J domain-containing protein djlC
Inner Membrane Lipoprotein
E
N/A
Cell membrane | Lipid-anchor
-
 
 
SEC
 
LOL
no
yes
YPDI_ECOLI
O32528
ypdI
b2376 JW2373
Uncharacterized lipoprotein ypdI
Outer Membrane Lipoprotein
I
N/A
Cell membrane | Lipid-anchor
Outer membrane Lipoprotein
 
 
SEC
 
LOL
no
yes
YFJS_ECOLI
O52982
yfjS
b2636 JW5921
Uncharacterized lipoprotein yfjS
Inner Membrane Lipoprotein
E
N/A
Cell membrane | Lipid-anchor
Inner membrane lipoprotein
 
 
SEC
 
LOL
no
no
SODM_ECOLI
P00448
sodA
b3908 JW3879
Superoxide dismutase [Mn] (EC 1.15.1.1) (MnSOD)
Periplasmic
G
N/A
 
Cytoplasmic
 
 
SEC, non classical
 
 
yes
yes
PPB_ECOLI
P00634
phoA
b0383 JW0374
Alkaline phosphatase (APase) (EC 3.1.3.1)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
DSBA
 
no
yes
ASPG2_ECOLI
P00805
ansB
b2957 JW2924
L-asparaginase 2 (EC 3.5.1.1) (L-asparaginase II) (L-ASNase II) (L-asparagine amidohydrolase II) (Colaspase)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
AMPC_ECOLI
P00811
ampC

ampA

b4150 JW4111
Beta-lactamase (EC 3.5.2.6) (Cephalosporinase)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
ARAF_ECOLI
P02924
araF
b1901 JW1889
L-arabinose-binding periplasmic protein (ABP)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
RBSB_ECOLI
P02925
rbsB

prlB rbsP

b3751 JW3730
D-ribose-binding periplasmic protein
Periplasmic
G
Soluble IM Fraction
Periplasm
Periplasmic (Experimental)
 
 
SEC
SKP
 
no
yes
TOLC_ECOLI
P02930
tolC

mtcB mukA refI

b3035 JW5503
Outer membrane protein tolC
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
SECB
SEC
SKP
BAM
yes
yes
OMPF_ECOLI
P02931
ompF

cmlB coa cry tolF

b0929 JW0912
Outer membrane protein F (Outer membrane protein 1A) (Outer membrane protein B) (Outer membrane protein IA) (Porin OmpF)
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
TF
SEC
SKP,SURA
BAM
yes
yes
PHOE_ECOLI
P02932
phoE

ompE

b0241 JW0231
Outer membrane pore protein E
Outer Membrane b-barrel protein
H
N/A
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
 
SEC
 
BAM
yes
yes
LAMB_ECOLI
P02943
lamB

malB

b4036 JW3996
Maltoporin (Lambda receptor protein) (Maltose-inducible porin)
Outer Membrane b-barrel protein
H
Soluble IM Fraction
Cell outer membrane | Multi-pass membrane protein
Outer Membrane β-barrel protein (Experimental)
 
 
SEC
SKP,SURA,DEGP
BAM
yes
yes
MALM_ECOLI
P03841
malM

molA

b4037 JW3997
Maltose operon periplasmic protein
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
FIMA1_ECOLI
P04128
fimA

pilA

b4314 JW4277
Type-1 fimbrial protein, A chain (Type-1A pilin)
Peripheral outer membrane protein facing the extra-cellular space
F4
N/A
Fimbrium
Cell surface appendage (Experimental)
fimbriae
 
SEC
 
CU
yes
yes
LIVK_ECOLI
P04816
livK
b3458 JW3423
Leucine-specific-binding protein (L-BP) (LS-BP)
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
DSBA
 
yes
yes
NLPA_ECOLI
P04846
nlpA
b3661 JW3635
Lipoprotein 28
Inner Membrane Lipoprotein
E
Soluble IM Fraction
Cell inner membrane | Lipid-anchor
Inner membrane lipoprotein
 
 
SEC
 
LOL
yes
yes
FLIC_ECOLI
P04949
fliC

flaF hag

b1923 JW1908
Flagellin
Peripheral outer membrane protein facing the extra-cellular space
F4
Soluble IM Fraction
SecretedBacterial flagellum
Cell surface appendage (Experimental)
flagellum
 
Flagellum
 
Fla
no
yes
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